GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sqstm1 | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of SQSTM1 mRNA; Carbon Tetrachloride results in increased expression of SQSTM1 protein | PMID:27339419 PMID:31919559 | Sqstm1 | multiple interactions | EXP | | 6480464 | CTD | [TRP53BP2 protein affects the susceptibility to Carbon Tetrachloride] which affects the expression of SQSTM1 protein; Carbon Tetrachloride results in increased expression of and results in increased phosphorylation of SQSTM1 protein; TRP53BP2 protein affects the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 protein] | PMID:31513885 PMID:35405287 | Sqstm1 | increases expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of SQSTM1 mRNA; Carbon Tetrachloride results in increased expression of SQSTM1 protein | PMID:26882442 PMID:31150632 | Sqstm1 | multiple interactions | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | Melatonin inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 protein]; schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 mRNA] | PMID:26882442 PMID:31150632 | | ||||||||||||||||||||||
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