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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735742
Species: Mus musculus
RGD Object: Gene
Symbol: Ccnb1
Name: cyclin B1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnb1increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of CCNB1 mRNA; Carbon Tetrachloride results in increased expression of CCNB1 proteinPMID:17484886 PMID:19887370 PMID:25747392 PMID:27339419 PMID:29987408 PMID:31919559
Ccnb1multiple interactionsEXP 6480464CTDalisol B 23-acetate promotes the reaction [Carbon Tetrachloride results in increased expression of CCNB1 mRNA]; alisol B 23-acetate promotes the reaction [Carbon Tetrachloride results in increased expression of CCNB1 protein]; Chenodeoxycholic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of CCNB1 mRNA]; PLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCNB1 mRNA]PMID:16006527 PMID:25747392
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