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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70981
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bco1
Name: beta-carotene oxygenase 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bco1decreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of BCO1 mRNAPMID:31150632
Bco1multiple interactionsEXP 6480464CTDschizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCO1 mRNA]PMID:31150632
Bco1decreases expressionISOBco1 (Mus musculus)6480464CTDCarbon Tetrachloride results in decreased expression of BCO1 mRNAPMID:17484886
Bco1increases expressionISOBco1 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of BCO1 mRNAPMID:27339419 PMID:31919559
Bco1multiple interactionsISOBco1 (Mus musculus)6480464CTD[Carbon Tetrachloride co-treated with Ethanol] results in increased expression of BCO1 mRNAPMID:30517762
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