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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69144
Species: Homo sapiens
RGD Object: Gene
Symbol: NFIA
Name: nuclear factor I A
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFIAdecreases expressionISONfia (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in decreased expression of NFIA mRNAPMID:30690589 PMID:30723492 PMID:31150632
NFIAincreases methylationISONfia (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in increased methylation of NFIA promoterPMID:30690589
NFIAmultiple interactionsISONfia (Rattus norvegicus)6480464CTDschizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFIA mRNA]PMID:31150632
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