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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62191
Species: Mus musculus
RGD Object: Gene
Symbol: Maoa
Name: monoamine oxidase A
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maoaincreases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of MAOA mRNA; Carbon Tetrachloride results in increased expression of MAOA proteinPMID:27339419 PMID:31919559 PMID:35202708
Maoamultiple interactionsEXP 6480464CTD[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]]PMID:35202708
Maoaincreases expressionISOMAOA (Homo sapiens)6480464CTDCarbon Tetrachloride results in increased expression of MAOA mRNA; Carbon Tetrachloride results in increased expression of MAOA proteinPMID:35202708
Maoamultiple interactionsISOMAOA (Homo sapiens)6480464CTDCarbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in increased expression of BAX protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]; MAOA protein affects the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]PMID:35202708
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