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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621475
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il11
Name: interleukin 11
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il11multiple interactionsEXP 6480464CTDIL11 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; IL11 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; IL11 protein promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [IL11 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]]; tin mesoporphyrin inhibits the reaction [IL11 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]]PMID:16964402
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