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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621157
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Txn1
Name: thioredoxin 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txn1decreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of TXN1 mRNAPMID:33387578
Txn1increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of TXN mRNAPMID:17522070
Txn1decreases expressionISOTxn1 (Mus musculus)6480464CTDCarbon Tetrachloride results in decreased expression of TXN protein; Carbon Tetrachloride results in decreased expression of TXN1 mRNAPMID:25471833 PMID:34029542
Txn1increases expressionISOTxn1 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of TXN1 mRNAPMID:31919559
Txn1multiple interactionsISOTxn1 (Mus musculus)6480464CTDganoderic acid A inhibits the reaction [Carbon Tetrachloride results in decreased expression of TXN protein]; Quercetin inhibits the reaction [Carbon Tetrachloride results in decreased expression of TXN1 mRNA]PMID:25471833 PMID:34029542
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