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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62089
Species: Mus musculus
RGD Object: Gene
Symbol: Prkn
Name: parkin RBR E3 ubiquitin protein ligase
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prknincreases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of PRKN proteinPMID:35405287
Prknmultiple interactionsEXP 6480464CTDSirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PRKN protein]PMID:35405287
Prkndecreases expressionISOPrkn (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in decreased expression of PRKN proteinPMID:26882442
Prknmultiple interactionsISOPrkn (Rattus norvegicus)6480464CTDMelatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKN protein]PMID:26882442
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