GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hif1a | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of HIF1A mRNA; Carbon Tetrachloride results in increased expression of HIF1A protein | PMID:16713642 PMID:23845850 | Hif1a | multiple interactions | EXP | | 6480464 | CTD | Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A protein] | PMID:23845850 | Hif1a | increases expression | ISO | Hif1a (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of HIF1A protein | PMID:36126797 | Hif1a | multiple interactions | ISO | Hif1a (Mus musculus) | 6480464 | CTD | HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL3 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL4 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CXCL1 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CXCL2 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP13 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of PLAU mRNA]; HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA] | PMID:24639359 | | ||||||||||||||||||||||
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