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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3438
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 synthase
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgisdecreases expressionEXP 6480464CTDCarbon Tetrachloride results in decreased expression of PTGIS mRNAPMID:30723492
Ptgisincreases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of PTGIS mRNAPMID:16644059
Ptgisaffects expressionISOPtgis (Mus musculus)6480464CTDCarbon Tetrachloride affects the expression of PTGIS mRNAPMID:17484886
Ptgismultiple interactionsISOPtgis (Mus musculus)6480464CTD[Carbon Tetrachloride co-treated with Ethanol] results in increased expression of PTGIS mRNAPMID:30517762
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