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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604061
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL5
Name: C-C motif chemokine ligand 5
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL5affects expressionISOCcl5 (Rattus norvegicus)6480464CTDCarbon Tetrachloride affects the expression of CCL5 mRNAPMID:15963342
CCL5decreases expressionISOCcl5 (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in decreased expression of CCL5 mRNAPMID:16239168 PMID:31150632
CCL5increases expressionISOCcl5 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of CCL5 mRNA; Carbon Tetrachloride results in increased expression of CCL5 proteinPMID:17412915 PMID:31919559 PMID:36555680
CCL5multiple interactionsISOCcl5 (Mus musculus)6480464CTDIvermectin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL5 mRNA]PMID:36555680
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