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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312509
Species: Homo sapiens
RGD Object: Gene
Symbol: HDAC2
Name: histone deacetylase 2
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13125106480464CTDCarbon Tetrachloride results in increased expression of HDAC2 mRNA, Carbon Tetrachloride results in increased expression of HDAC2 protein

PMID:27396813
multiple interactionsISORGD:13125106480464CTDCarbon Tetrachloride deficiency inhibits the reaction [Carbon Tetrachloride results in increased expression of HDAC2 mRNA], Carbon Tetrachloride deficiency inhibits the reaction [Carbon Tetrachloride results in increased expression of HDAC2 protein]

PMID:27396813
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.