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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730944
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCB11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:27375
Term: vincaleukoblastine
Definition: A vinca alkaloid that has formula C46H58N4O9.
Chemical ID: MESH:D014747
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCB11decreases activityEXP 6480464CTDVinblastine results in decreased activity of ABCB11 proteinPMID:24014644
ABCB11multiple interactionsEXP 6480464CTDVinblastine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]PMID:24014644
ABCB11decreases uptakeISOAbcb11 (Mus musculus)6480464CTDABCB11 protein results in decreased uptake of VinblastinePMID:10617675
ABCB11increases exportISOAbcb11 (Mus musculus)6480464CTDABCB11 protein results in increased export of VinblastinePMID:10617675
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