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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733809
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC6A3
Name: solute carrier family 6 member 3
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC6A3decreases activityEXP 6480464CTDZinc results in decreased activity of SLC6A3 proteinPMID:16684900
SLC6A3multiple interactionsEXP 6480464CTD[Amphetamine co-treated with Zinc] results in decreased localization of SLC6A3 proteinPMID:16684900
SLC6A3increases expressionISOSlc6a3 (Rattus norvegicus)6480464CTDZinc results in increased expression of SLC6A3 proteinPMID:32060784
SLC6A3multiple interactionsISOSlc6a3 (Rattus norvegicus)6480464CTDParaquat promotes the reaction [Zinc results in increased expression of SLC6A3 protein]; Zinc promotes the reaction [Paraquat results in increased expression of SLC6A3 protein]PMID:32060784
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