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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733315
Species: Mus musculus
RGD Object: Gene
Symbol: Il2
Name: interleukin 2
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il2affects localizationEXP 6480464CTDIL2 protein affects the localization of ZincPMID:20201035
Il2affects expressionISOIL2 (Homo sapiens)6480464CTDZinc affects the expression of IL2 mRNA; Zinc affects the expression of IL2 proteinPMID:16930873
Il2decreases expressionISOIl2 (Rattus norvegicus)6480464CTDZinc deficiency results in decreased expression of IL2 mRNAPMID:12672911
Il2decreases expressionISOIL2 (Homo sapiens)6480464CTDZinc deficiency results in decreased expression of IL2PMID:12389026
Il2increases expressionISOIL2 (Homo sapiens)6480464CTDZinc results in increased expression of IL2 mRNA; Zinc results in increased expression of IL2 proteinPMID:17162254 PMID:18842795
Il2multiple interactionsISOIL2 (Homo sapiens)6480464CTDZinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]PMID:12812920
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