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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732739
Species: Homo sapiens
RGD Object: Gene
Symbol: ARNT
Name: aryl hydrocarbon receptor nuclear translocator
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ARNTdecreases localizationEXP 6480464CTDZinc results in decreased localization of ARNT proteinPMID:11739637
ARNTmultiple interactionsEXP 6480464CTD[Zinc results in decreased localization of ARNT protein] inhibits the reaction [ARNT protein binds to HIF1A protein]; [Zinc results in increased expression of HIF1A mRNA alternative form] which results in decreased localization of ARNT protein; Zinc inhibits the reaction [ARNT protein binds to HIF1A protein]PMID:11739637
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