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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731414
Species: Mus musculus
RGD Object: Gene
Symbol: Grk1
Name: G protein-coupled receptor kinase 1
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grk1decreases expressionISOGrk1 (Rattus norvegicus)6480464CTDZinc results in decreased expression of GRK1 proteinPMID:16799065
Grk1multiple interactionsISOGrk1 (Rattus norvegicus)6480464CTD6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc results in decreased expression of GRK1 protein]; Metipranolol inhibits the reaction [Zinc results in decreased expression of GRK1 protein]PMID:16799065
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