GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP9 | multiple interactions | EXP | | 6480464 | CTD | [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein; [PCI 5002 co-treated with Zinc] results in increased expression of CASP9 mRNA; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein] | PMID:18593933 PMID:29115570 | CASP9 | decreases expression | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | Zinc results in decreased expression of CASP9 protein | PMID:32060784 | CASP9 | multiple interactions | ISO | Casp9 (Rattus norvegicus) | 6480464 | CTD | [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Paraquat promotes the reaction [Zinc results in decreased expression of CASP9 protein]; Zinc affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]; Zinc promotes the reaction [Paraquat results in decreased expression of CASP9 protein] | PMID:24184500 PMID:32060784 | |
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