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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2690
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gja1
Name: gap junction protein, alpha 1
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gja1decreases expressionEXP 6480464CTDZinc results in decreased expression of GJA1 mRNAPMID:17074742
Gja1increases expressionEXP 6480464CTDZinc deficiency results in increased expression of GJA1 mRNA; Zinc deficiency results in increased expression of GJA1 protein; Zinc results in increased expression of GJA1 mRNAPMID:15159208 PMID:18224284 PMID:19111725
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