Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552027
Species: Mus musculus
RGD Object: Gene
Symbol: Ep300
Name: E1A binding protein p300
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ep300multiple interactionsEXP 6480464CTD[Zinc promotes the reaction [MTF1 protein binds to EP300 protein]] which results in increased expression of MT1 mRNA; chromium hexavalent ion inhibits the reaction [Zinc promotes the reaction [MTF1 protein binds to EP300 protein]]; EP300 protein affects the reaction [Zinc results in increased expression of MT1 mRNA]; EP300 protein inhibits the reaction [chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1 mRNA]]; Zinc promotes the reaction [MTF1 protein binds to EP300 protein binds to CREBBP protein]; Zinc promotes the reaction [MTF1 protein binds to EP300 protein]; Zinc promotes the reaction [MTF1 protein promotes the reaction [EP300 protein binds to SP1 protein]]PMID:18458062 PMID:18605988 PMID:21035574 PMID:21467744
Ep300affects expressionISOEP300 (Homo sapiens)6480464CTDZinc affects the expression of EP300 proteinPMID:16636310
Go Back to source page   Continue to Ontology report