GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | increases expression | EXP | | 6480464 | CTD | Zinc results in increased expression of HSPA1A mRNA | PMID:16870260 PMID:17244614 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | [PCI 5002 co-treated with Zinc] results in increased expression of HSPA1A mRNA; Zinc promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Zinc promotes the reaction [HSF1 protein binds to HSPA1A promoter] | PMID:16460681 PMID:17244614 PMID:18593933 | HSPA1A | increases expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | Zinc results in increased expression of HSPA1A mRNA; Zinc results in increased expression of HSPA1A protein | PMID:15159208 PMID:16949620 | |
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