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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305906
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lats2
Name: large tumor suppressor kinase 2
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lats2affects bindingISOLATS2 (Homo sapiens)6480464CTDZinc binds to LATS2 proteinPMID:35027733
Lats2multiple interactionsISOLATS2 (Homo sapiens)6480464CTD[PCI 5002 co-treated with Zinc] results in increased expression of LATS2 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to LATS2 protein]PMID:18593933 PMID:35027733
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