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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:27086
Term: tributylstannane
Definition: An organotin compound that has formula C12H28Sn.
Chemical ID: MESH:C011559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:694736480464CTDtributyltin results in increased expression of SREBF1 mRNA

PMID:28011154
increases expressionISORGD:694746480464CTDtributyltin results in increased expression of SREBF1 mRNA

PMID:23322813, PMID:25932594
multiple interactionsISORGD:694736480464CTDtributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]

PMID:25932594
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.