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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68534
Species: Mus musculus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:27086
Term: tributylstannane
Definition: An organotin compound that has formula C12H28Sn.
Chemical ID: MESH:C011559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases expressionISOMtor (Rattus norvegicus)6480464CTDtributyltin results in decreased expression of MTORPMID:26961604
Mtordecreases phosphorylationISOMtor (Rattus norvegicus)6480464CTDtributyltin results in decreased phosphorylation of MTOR proteinPMID:20371977
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