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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631377
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sp7
Name: Sp7 transcription factor
Acc ID: CHEBI:27086
Term: tributylstannane
Definition: An organotin compound that has formula C12H28Sn.
Chemical ID: MESH:C011559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sp7decreases expressionISOSp7 (Mus musculus)6480464CTDtributyltin results in decreased expression of SP7 mRNAPMID:25777084 PMID:25932594
Sp7multiple interactionsISOSP7 (Homo sapiens)6480464CTDtributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]PMID:25932594
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