Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	10289
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Casp3
Name:	caspase 3

Acc ID:	CHEBI:2682
Term:	amphotericin B
Definition:	A macrolide antibiotic used to treat potentially life-threatening fungal infections.
Chemical ID:	MESH:D000666

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Casp3	increases expression	EXP		6480464	CTD	Amphotericin B results in increased expression of CASP3 protein	PMID:23988732

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.