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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tp53
Name: tumor protein p53
Acc ID: CHEBI:2674
Term: amodiaquine
Definition: A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Chemical ID: MESH:D000655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tp53affects expressionISOTP53 (Homo sapiens)6480464CTDAmodiaquine affects the expression of TP53 proteinPMID:24113242
Tp53increases activityISOTP53 (Homo sapiens)6480464CTDAmodiaquine results in increased activity of TP53 proteinPMID:12082016
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