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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323231
Species: Homo sapiens
RGD Object: Gene
Symbol: PDCD1
Name: programmed cell death 1
Acc ID: CHEBI:2674
Term: amodiaquine
Definition: A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Chemical ID: MESH:D000655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDCD1multiple interactionsISOPdcd1 (Mus musculus)6480464CTD[PDCD1 protein co-treated with LAG3 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; [PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]; CTLA4 protein affects the reaction [[PDCD1 protein co-treated with TGFB1 protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]; CTLA4 protein affects the reaction [PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]]; PDCD1 protein affects the reaction [[LY6C1 protein co-treated with LY6G protein] affects the reaction [Amodiaquine results in increased expression of GPT protein]]PMID:29938495
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