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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734432
Species: Mus musculus
RGD Object: Gene
Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Acc ID: CHEBI:26718
Term: solanesol
Definition: A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer).
Chemical ID: MESH:C017719
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsISORGD:7344316480464CTDsolanesol affects the localization of and results in increased activity of NFE2L2 protein; solanesol inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]; solanesol results in decreased ubiquitination of and results in decreased degradation of NFE2L2 proteinPMID:25645596
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