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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289
Species: Mus musculus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:26718
Term: solanesol
Definition: A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer).
Chemical ID: MESH:C017719
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTD2-phenylacetylenesulfonamide inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; solanesol promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]; tin protoporphyrin IX inhibits the reaction [solanesol inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]]PMID:25645596
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