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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12388002
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:26710
Term: sodium chloride
Definition: An inorganic chloride salt having sodium(1+) as the counterion.
Chemical ID: MESH:D012965
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3increases phosphorylationEXP 6480464CTDSodium Chloride results in increased phosphorylation of MAPK3 proteinPMID:23816505
MAPK3multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]PMID:23816505
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