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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:26709
Term: sodium hydrogensulfite
Definition: An inorganic sodium salt having hydrogensulfite as the counterion.
Chemical ID: MESH:C009279
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTD6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; [sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; KT 5720 inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]PMID:21873648
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