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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735721
Species: Mus musculus
RGD Object: Gene
Symbol: Kcns1
Name: K+ voltage-gated channel, subfamily S, 1
Acc ID: CHEBI:2666
Term: amitriptyline
Definition: An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Chemical ID: MESH:D000639
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:6215246480464CTDAmitriptyline results in decreased expression of KCNS1 mRNA

PMID:22341215
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.