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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733240
Species: Mus musculus
RGD Object: Gene
Symbol: Pon1
Name: paraoxonase 1
Acc ID: CHEBI:26596
Term: salicylates
Definition: Any salt or ester arising from reaction of the carboxy group of salicylic acid, or any ester resulting from the condensation of the phenolic hydroxy group of salicylic acid with an organic acid.
Chemical ID: MESH:D012459
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pon1increases activityISOPON1 (Homo sapiens)6480464CTDSalicylates results in increased activity of PON1 proteinPMID:18519978
Pon1increases expressionISOPON1 (Homo sapiens)6480464CTDSalicylates results in increased expression of PON1 mRNAPMID:18519978
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