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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731284
Species: Homo sapiens
RGD Object: Gene
Symbol: HSD17B4
Name: hydroxysteroid 17-beta dehydrogenase 4
Acc ID: CHEBI:2654
Term: aminoglutethimide
Definition: A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Chemical ID: MESH:D000616
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSD17B4decreases expressionEXP 6480464CTDAminoglutethimide results in decreased expression of HSD17B4 mRNAPMID:16935330
HSD17B4multiple interactionsEXP 6480464CTDAminoglutethimide inhibits the reaction [Colforsin results in increased expression of HSD17B4 mRNA]PMID:16935330
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