GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il2 | increases expression | ISO | IL2 (Homo sapiens) | 6480464 | CTD | Reactive Oxygen Species results in increased expression of IL2 mRNA | PMID:22429591 | Il2 | multiple interactions | ISO | IL2 (Homo sapiens) | 6480464 | CTD | [6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of IL2 mRNA; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of IL2 mRNA; [SOD2 protein results in decreased abundance of Reactive Oxygen Species] which results in decreased secretion of IL2 protein; SOD2 protein inhibits the reaction [Reactive Oxygen Species results in increased expression of IL2] | PMID:22429591 | |
Go Back to source page | Continue to Ontology report |