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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71019
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Egln3
Name: egl-9 family hypoxia-inducible factor 3
Acc ID: CHEBI:26523
Term: reactive oxygen species
Definition: Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Chemical ID: MESH:D017382
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egln3multiple interactionsISOEGLN3 (Homo sapiens)6480464CTD[[Reactive Oxygen Species results in increased oxidation of dimethylselenide] which results in increased expression of DLGAP1-AS2 mRNA] which results in decreased expression of EGLN3 mRNAPMID:33656867
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