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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10708
Species: Mus musculus
RGD Object: Gene
Symbol: Hgf
Name: hepatocyte growth factor
Acc ID: CHEBI:26523
Term: reactive oxygen species
Definition: Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Chemical ID: MESH:D017382
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hgfmultiple interactionsEXP 6480464CTDHGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species]PMID:23764483
Hgfincreases expressionISOHgf (Rattus norvegicus)6480464CTDReactive Oxygen Species results in increased expression of HGF mRNAPMID:15672869
Hgfmultiple interactionsISOHgf (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [Reactive Oxygen Species results in increased expression of HGF mRNA]PMID:15672869
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