GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Scnn1a | affects activity | EXP | | 6480464 | CTD | Amiloride affects the activity of SCNN1A protein | PMID:8617496 | Scnn1a | multiple interactions | ISO | Scnn1a (Rattus norvegicus) | 6480464 | CTD | [farglitazar co-treated with Amiloride] results in increased expression of SCNN1A mRNA | PMID:15475592 | Scnn1a | multiple interactions | ISO | SCNN1A (Homo sapiens) | 6480464 | CTD | Amiloride inhibits the reaction [[SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Sodium]; Amiloride results in decreased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D]; Amiloride results in decreased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] | PMID:18398334 PMID:18665318 PMID:19359370 | |
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