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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736082
Species: Mus musculus
RGD Object: Gene
Symbol: Adra1a
Name: adrenergic receptor, alpha 1a
Acc ID: CHEBI:26216
Term: potassium atom
Definition: An alkali metal atom that has formula K.
Chemical ID: MESH:D011188
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adra1amultiple interactionsISOAdra1a (Rattus norvegicus)6480464CTD[Phenylephrine affects the activity of ADRA1A protein] which affects the transport of PotassiumPMID:19133277
Adra1amultiple interactionsISOADRA1A (Homo sapiens)6480464CTD[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] affects the reaction [[Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium]; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium; [Phenylephrine results in increased activity of ADRA1A protein] which affects the transport of Potassium; KT 5720 inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]; Prazosin inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]; Ro 32-0432 inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]PMID:15365637 PMID:19419905
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