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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2060
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adrb2
Name: adrenoceptor beta 2
Acc ID: CHEBI:26216
Term: potassium atom
Definition: An alkali metal atom that has formula K.
Chemical ID: MESH:D011188
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adrb2multiple interactionsISOADRB2 (Homo sapiens)6480464CTD[[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium]; [Albuterol binds to and results in increased activity of ADRB2 protein] which results in decreased abundance of Potassium; [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased abundance of Potassium; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of PotassiumPMID:17292646 PMID:19419905 PMID:8102213
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