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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10438
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:2607
Term: Aloe emodin
Definition: A dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe.
Chemical ID: MESH:C518327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2decreases activityISOCYP1A2 (Homo sapiens)6480464CTDaloe emodin results in decreased activity of CYP1A2 proteinPMID:27633141 PMID:33438235
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