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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736452
Species: Homo sapiens
RGD Object: Gene
Symbol: FMO1
Name: flavin containing dimethylaniline monoxygenase 1
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FMO1decreases expressionISOFmo1 (Mus musculus)6480464CTDOzone results in decreased expression of FMO1 mRNAPMID:12763052
FMO1multiple interactionsISOFmo1 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of FMO1 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of FMO1 mRNAPMID:34911549
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