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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 7240857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trim34
Name: tripartite motif-containing 34
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trim34multiple interactionsISOTrim34a (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TRIM34A mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of TRIM34 mRNAPMID:25658374 PMID:34911549
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