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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70970
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmgcs1
Name: 3-hydroxy-3-methylglutaryl-CoA synthase 1
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgcs1decreases expressionEXP 6480464CTDOzone results in decreased expression of HMGCS1 mRNAPMID:16716893 PMID:33217375 PMID:33524448
Hmgcs1multiple interactionsEXP 6480464CTDOzone inhibits the reaction [Fish Oils results in increased expression of HMGCS1 mRNA]PMID:33217375
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