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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621059
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccna2
Name: cyclin A2
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccna2multiple interactionsISOCCNA2 (Homo sapiens)6480464CTD[Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of CCNA2 mRNA; [Oxygen co-treated with Ozone] results in decreased expression of CCNA2 mRNAPMID:32992648
Ccna2multiple interactionsISOCcna2 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of CCNA2 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CCNA2 mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of CCNA2 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CCNA2 mRNA]PMID:19555225 PMID:25658374 PMID:27106289 PMID:34911549
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