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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620143
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pitpnb
Name: phosphatidylinositol transfer protein, beta
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pitpnbincreases expressionEXP 6480464CTDOzone results in increased expression of PITPNB mRNAPMID:35737395
Pitpnbmultiple interactionsISOPITPNB (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PITPNB mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PITPNB mRNA; [Air Pollutants results in increased abundance of Ozone] which affects the expression of PITPNB mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased oxidation of PITPNB mRNAPMID:32699268 PMID:35430440
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