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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2906
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcr2
Name: C-X-C motif chemokine receptor 2
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcr2multiple interactionsISOCXCR2 (Homo sapiens)6480464CTD[Air Pollutants results in increased abundance of Ozone] which affects the expression of CXCR2 mRNAPMID:35430440
Cxcr2multiple interactionsISOCxcr2 (Mus musculus)6480464CTDOzone promotes the reaction [CXCR2 protein affects the susceptibility to Methacholine Chloride]PMID:15361358
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