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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2598
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ms4a2
Name: membrane spanning 4-domains A2
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pleasant odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects response to substanceISORGD:13500656480464CTDMS4A2 gene SNP affects the susceptibility to Ozone

PMID:18269668
multiple interactionsISORGD:13500656480464CTDGSTM1 gene SNP affects the reaction [MS4A2 gene SNP affects the susceptibility to Ozone], GSTP1 gene SNP affects the reaction [MS4A2 gene SNP affects the susceptibility to Ozone]

PMID:18269668
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.