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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2321145
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fbxw7
Name: F-box and WD repeat domain containing 7
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxw7multiple interactionsISOFBXW7 (Homo sapiens)6480464CTD[[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of FBXW7-AS1 mRNA] which results in increased expression of FBXW7 mRNA; [Air Pollutants results in increased abundance of Ozone] which affects the expression of FBXW7 mRNAPMID:33656867 PMID:35430440
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